B.1.4 Old myocardial infarct with aneurysmal dilatation of the apex

  • The aorta shows atheromatous plaques just above the aortic cusps.
  • The left ventricular wall shows hypertrophy.
  • At the apex, on the pericardial and the endocardial surfaces there are blotchy areas.
  • The white blotches probably are either fibrosed or calcified spots.
  • There is aneurysmal dilatation of the wall at the apex.
  • The coronary arteries show narrowing and are of irregular caliber.

 

Clinical presentation

A 68-year-old man was admitted to the emergency unit with severe chest pain for one hour. Despite treatment, he died eight hours following admission. He is a known patient with poorly controlled hypertension for 15 years. He has a history of a myocardial infarction one year ago. 

A postmortem was performed.

The specimen (B 1.4) displays the cut opened left ventricle of his heart.

Macroscopic changes

Describe the macroscopic changes you observe in his heart.

  • There is left ventricular wall hypertrophy.
  • The apex shows aneurysmal dilatation (see Arrow, Image 1) and pale colour myocardium, probably fibrosed foci related to the previous infarct.
  • Atheromatous plaques are noted just above the aortic cusps.

Aneurysmal dilatation

Image 1 - Aneurysmal dilatation

Microscopic changes

What are the microscopic changes you expect to see in the different macroscopic pathologies described above?

Hypertrophic myocardium - variable degrees of cellular and nuclear enlargement and interstitial fibrosis

Old infarct - collagenous scar tissue  

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